Bloomsburg is a town in Columbia County, Pennsylvania, United States, located 40 miles southwest of Wilkes-Barre along the Susquehanna River. It is the county seat of Columbia County and the only incorporated town in Pennsylvania. As of the 2010 census, Bloomsburg had a population of 14,855, with an estimated population of 14,519 in 2013.Bloomsburg is one of two principal communities of the Bloomsburg-Berwick, PA Micropolitan Statistical Area, a micropolitan area that covers Columbia and Montour counties, and had a combined population of 85,562 at the 2010 census.